Classification of TB skin test reactions

An induration of 5 or more millimeters is considered positive in:

  • People with HIV

  • Recent contacts of people with infectious TB disease

  • People with chest x-ray findings suggestive of previous TB disease

  • People with organ transplants

  • Other immunosuppressed people (e.g., patients on prolonged therapy with corticosteroids equivalent to/greater than 15 mg per day of prednisone or those taking TNF-α antagonists)

An induration of 10 or more millimeters is considered positive in:

  • People born in countries where TB disease is common, including some countries in Asia, Africa, and Latin America

  • People who misuse drugs and alcohol

  • People who live or work in high-risk congregate settings (e.g. nursing homes, homeless shelters, or correctional facilities)

  • Mycobacteriology laboratory workers

  • People with certain medical conditions that place them at high risk for TB (e.g. silicosis, diabetes mellitus, severe kidney disease, certain types of cancer, or certain intestinal conditions)

  • People with a low body weight (<90% of ideal body weight)

  • Children younger than 5 years of age

  • Infants, children, and adolescents exposed to adults in high-risk categories

An induration of 15 or more millimeters is considered positive in:

  • People with no known risk factors for TB