Cardiovascular
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Chest pain (the single most common ED diagnosis overall, ~4.3–5.5% of all visits)
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Acute coronary syndromes (STEMI, NSTEMI, unstable angina)
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Heart failure / acute decompensated heart failure (~5.7% of emergency care–sensitive visits)
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Cardiac arrest and severe arrhythmias (leading cause of ED mortality, 58–77% of ED deaths)
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Hypertensive emergencies
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Aortic aneurysm and dissection
Respiratory
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COPD exacerbation (~7.9% of emergency care–sensitive visits)
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Pneumonia (~7.9%)
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Asthma exacerbation (~6.1%)
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Shortness of breath / dyspnea (~3.7% of chief complaints; ~12% in European data)
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Upper respiratory infections
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Respiratory failure (88% admission rate when present)
Gastrointestinal
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Abdominal pain (the most common overall chief complaint in many datasets, ~7–12% of all visits)2(https://pubmed.ncbi.nlm.nih.gov/30704822)[[3]](https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50522?utm_source=openevidence&utm_medium=referral)
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Nausea and vomiting (~2.9% of chief complaints)3(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50522?utm_source=openevidence&utm_medium=referral)
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Acute appendicitis4(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2019.8642?utm_source=openevidence&utm_medium=referral)
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GI bleeding
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Biliary disease (cholecystitis, cholelithiasis)
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Bowel obstruction
Neurologic
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Headache (~1.7–2.8% of visits)3(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50522?utm_source=openevidence&utm_medium=referral)
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Stroke / TIA
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Seizures
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Syncope / presyncope
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Altered mental status (~6.6% of visits in triage data)6(https://onlinelibrary.wiley.com/doi/10.1111/jocn.70320)
Musculoskeletal / Trauma
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Sprains and strains4(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2019.8642?utm_source=openevidence&utm_medium=referral)
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Fractures
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Joint pain (~2.3% of discharge diagnoses)3(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50522?utm_source=openevidence&utm_medium=referral)
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Extremity pain (~1.5%)3(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50522?utm_source=openevidence&utm_medium=referral)
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Back pain (~2.8% of chief complaints)3(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50522?utm_source=openevidence&utm_medium=referral)
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Falls (a leading chief complaint, especially in older adults)7(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.37557?utm_source=openevidence&utm_medium=referral)
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Trauma-related conditions (~21% of all ED visits in triage-based data)6(https://onlinelibrary.wiley.com/doi/10.1111/jocn.70320)
Genitourinary
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Urinary tract infections (~1.8–2.6% of visits; more common in women)1(https://pubmed.ncbi.nlm.nih.gov/42425740)[[3]](https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50522?utm_source=openevidence&utm_medium=referral)
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Renal colic / nephrolithiasis
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Acute urinary retention
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Testicular torsion / ovarian torsion
Infectious Disease / Systemic
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Sepsis / SIRS (the most common emergency care–sensitive condition, ~10.7%; 95% admission rate)4(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2019.8642?utm_source=openevidence&utm_medium=referral)
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COVID-19 (became the single most common ED diagnosis in 2021 at 4.8%)1(https://pubmed.ncbi.nlm.nih.gov/42425740)
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Fever (~8% of chief complaints)5(https://pubmed.ncbi.nlm.nih.gov/36409936)
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Cellulitis / skin and soft tissue infections
Psychiatric / Behavioral
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Mental health problems, including suicidal ideation and psychosis (~4.5% of visits, the second most common category in some analyses)2(https://pubmed.ncbi.nlm.nih.gov/30704822)
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Substance use disorders / alcohol intoxication1(https://pubmed.ncbi.nlm.nih.gov/42425740)
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Self-harm (disproportionately affects younger adults)1(https://pubmed.ncbi.nlm.nih.gov/42425740)
Endocrine / Metabolic
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Acute diabetes complications (DKA, hypoglycemia — ranked in the top 10 emergency care–sensitive conditions across all age groups)4(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2019.8642?utm_source=openevidence&utm_medium=referral)
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Electrolyte abnormalities
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Adrenal crisis
Dermatologic
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Skin and soft tissue infections / abscesses (~3.5% in triage data)6(https://onlinelibrary.wiley.com/doi/10.1111/jocn.70320)
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Allergic reactions / urticaria / angioedema
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Lacerations requiring repair
Obstetric / Gynecologic
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Ectopic pregnancy4(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2019.8642?utm_source=openevidence&utm_medium=referral)
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Vaginal bleeding
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Pelvic pain
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Obstetric emergencies (though a small proportion of overall ED volume, ~0.4%)6(https://onlinelibrary.wiley.com/doi/10.1111/jocn.70320)
Key patterns to note: Abdominal pain and chest pain consistently rank as the top two chief complaints across national datasets.1(https://pubmed.ncbi.nlm.nih.gov/42425740)[[2]](https://pubmed.ncbi.nlm.nih.gov/30704822)[[3]](https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.50522?utm_source=openevidence&utm_medium=referral) Among conditions requiring admission, sepsis/SIRS, respiratory failure, and heart failure dominate.4(https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2019.8642?utm_source=openevidence&utm_medium=referral) Cardiac arrest is the overwhelming leading cause of ED mortality.1(https://pubmed.ncbi.nlm.nih.gov/42425740) Presentation patterns shift significantly by age — younger adults present more with trauma, respiratory infections, and self-harm, while older adults present more with sepsis, COPD, and pneumonia.1(https://pubmed.ncbi.nlm.nih.gov/42425740)
Would you like to explore how these ED presentation patterns differ across specific age groups or demographic populations?
References
- National Patterns in Emergency Department Diagnoses and Mortality: Insights From the Nationwide Emergency Department Sample. Goyal A, Quazi MA, Saeed H, et al. Emergency Medicine Journal : EMJ. 2026;:emermed-2026-215921. doi:10.1136/emermed-2026-215921.
- Characteristics and Trends of Emergency Department Visits in the United States (2010-2014). Hooker EA, Mallow PJ, Oglesby MM. The Journal of Emergency Medicine. 2019;56(3):344-351. doi:10.1016/j.jemermed.2018.12.025.
- Concordance in Medical Urgency Classification of Discharge Diagnoses and Reasons for Visit. Giannouchos TV, Ukert B, Wright B. JAMA Network Open. 2024;7(1):e2350522. doi:10.1001/jamanetworkopen.2023.50522.
- Identification of Emergency Care–Sensitive Conditions and Characteristics of Emergency Department Utilization. Vashi AA, Urech T, Carr B, et al. JAMA Network Open. 2019;2(8):e198642. doi:10.1001/jamanetworkopen.2019.8642.
- Chief Complaints, Underlying Diagnoses, and Mortality in Adult, Non-Trauma Emergency Department Visits: A Population-Based, Multicenter Cohort Study. Arvig MD, Mogensen CB, Skjøt-Arkil H, et al. The Western Journal of Emergency Medicine. 2022;23(6):855-863. doi:10.5811/westjem.2022.9.56332.
- Evaluation of Nurse‐Led Triage in the Emergency Department: A Retrospective Observational Study. Selva-Medrano D, Laredo-Aguilera JA, Serrano-Fernández V, et al. Journal of Clinical Nursing. 2026;. doi:10.1111/jocn.70320.
- Race and Ethnicity and Primary Language in Emergency Department Triage. Joseph JW, Kennedy M, Landry AM, et al. JAMA Network Open. 2023;6(10):e2337557. doi:10.1001/jamanetworkopen.2023.37557.