Shock Definition

  • Definition: Inadequate Tissue Perfusion to Meet End-Organ Needs
  • Cellular/Tissue Hypoxia from Reduced Oxygen Delivery, Increased Oxygen Consumption, or Inadequate Oxygen Utilization
  • Generally Caused by Circulatory Failure with Hypotension
    • Not Based Solely on Vital Signs
    • Can Present with Hypertension in Certain Cases

In other words: VO2 (oxygen consumption) > DO2 (oxygen delivery)

Shock Classifications

Distributive Shock: Severe Peripheral Vasodilation (50% – Most Common Cause)
- Septic Shock
- Systemic Inflammatory Response Syndrome (SIRS)
- Neurogenic Shock
- Anaphylactic Shock
- Endocrine Shock (Addisonian/Adrenal Crisis)
- Drug/Toxin-Induced Shock

Cardiogenic Shock: Cardiac Etiology Causing Reduced Cardiac Output (14%)

Hypovolemic Shock: From Reduced Intravascular Volume (31%)
- Hemorrhagic Shock
- Non-Hemorrhagic Hypovolemic Shock

Obstructive Shock: Extra-Cardiac Etiology of Cardiac Pump Failure (1%)

Mortality

  • Distributive Shock: 20-50%
    • Septic Shock: 40-50%
    • Neurogenic Shock: 13-23%
    • Endocrine Shock (Addisonian/Adrenal Crisis): 6%
  • Cardiogenic Shock: 50-75% (Highest Risk)
  • Hypovolemic Shock: 20-37%

Workup and Monitoring

Treatment Principles

The treatment of shock has three objectives:

  1.     Increase DO2
  2.     Decrease VO2
  3.     Treat the underlying cause